p42 MAPK (ERK2) Antibody(ICP0205)

Applications:
ELISA; WB; IP
Specificity:
The antibody recognizes human, rat, bovine, mouse and rabbit p42 ERK2. It does not cross-react with p44 ERK1.
Immunogen:
Human p42 ERK2 C-terminal peptide-KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in TBS, 50% glycerol, 0.01% NaN3
Pack Size
Price (USD)
Quantity
100 μg
$295.00
In Stock Request a Bulk Order
  • Product Description

    Affinity purified rabbit polyclonal anti-p42 MAPK antibodies are developed with the C-terminal peptide of human MAPK (ERK2).
  • Specificity

  • Applications

  • Scientific Description

    Maturation of mitogen-activated protein kinase (MAPK), also known as extracellular signal regulated kinase 2 (ERK2), is involved in the eukaryotic signalling process. [1] It is activated by a dual phosphorylation on threonine and tyrosine residues by the dual-specificity kinase MKK1/2. After stimulation, ERK2 p42 translocates to the nucleus. [2] Once phosphorylated, ERK2 can form dimers with phosphorylated and unphosphorylated ERK2 partners. ERK2 can also phosphorylate many substrates, for instance EGFR, c-PLA2, Elk1/TCF and c-Myc. [3-5]

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

  • Sample Data

    Affinity purified rabbit polyclonal anti-p42 MAPK antibodies are developed with the C-terminal peptide of human MAPK (ERK2).

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