Anti-dimethyl lysine antibody is developed using dimethylated KLH as immunogen, and purified with dimethyl lysine-agarose affinity chromatography. This antibody can be utilized for detection, quantification and isolation of proteins/peptides with dimethylated lysine residues.

Protein lysine methylation is a conserved post-translational modification and is an important biochemical process for many protein-protein interactions. It is found in many proteins, for example calmodulin, cytochrome C, chromosomal proteins, histones, non-histones as well as neural storage body proteins. It has been suggested that dimethylation of lysine plays an important role in gene silencing.[1]

Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is three years from date of shipping if stored properly.

1. Mol. BioSyst. 2013. 9: 2231-2247. doi: 10.1039/C3MB00009E