Dimethyl (ε-N) Lysine Antibody(ICP0701)

Applications:
ELISA, WB, IP
Specificity:
Specific to proteins/peptides with dimethyl lysine residues. No cross-reaction with acetylated lysine. Cross-reactivity to monomethyl lysine not tested.
Immunogen:
Dimethylated KLH
Species:
Rabbit
Formulation:
250 µg/mL in PBS, 50% glycerol
Pack Size
Price (USD)
Quantity
100 μg
$325.00
In Stock Request a Bulk Order
  • Product Description

    The anti-dimethyl lysine antibody is developed using dimethylated KLH as immunogen, and purified with dimethyl lysine-agarose affinity chromatography. The antibody can be utilized for detection, quantification and isolation of proteins/peptides with dimethylated lysine residues.
  • Specificity

  • Applications

  • Scientific Description

    Protein lysine methylation is a conserved post-translational modification and is an important biochemical process for many protein-protein interactions. It is found in many proteins, for example calmodulin, cytochrome C, chromosomal proteins, histones, non-histones as well as neural storage body proteins. It has been suggested that dimethylation of lysine plays an important role in gene silencing.[1]

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is three years from date of shipping if stored properly.

  • Product Specific References

    1. 1. Mol. BioSyst. 2013. 9: 2231-2247. doi: 10.1039/C3MB00009E
       
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