Acetyl Lysine Antibody, Mouse Monoclonal(ICP0390)

Applications:
ELISA; WB (0.1-0.5 µg/mL); IF (1-5 µg/mL); IP(approximately 10µg/mg crude protein)
Specificity:
The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA and acetylated MBP. No cross-reaction to non-acetylated proteins.
Immunogen:
Acetylated KLH conjugates
Species:
Mouse
Formulation:
250 μg/mL in PBS (pH7) with 50% glycerol
Isotype:
IgGa2
Pack Size
Price (USD)
Quantity
100ug
$350.00
In Stock Request a Bulk Order
  • Product Description

    The pan-specific anti-acetyl lysine monoclonal antibody is developed using hybridoma technology, and affinity purified with acetyl-lysine agarose. It recognizes both free acetyl-lysine and acetyl-lysine residues in proteins/peptides.
  • Scientific Description

    DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylating lysine residues within the proteins. It has been suggested that acetylation of non-histone proteins (e.g., transcription factors) and histones may be involved. Acetylation of these proteins may result in signal transduction within the chromatic domains.

  • Storage & Stability

    Product is stable for 30 days at room temperature. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored.

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