Dimethyl (asy) Arginine Antibody is raised from rabbits immunized with NG,NG-dimethyl arginine-KLH, and affinity purified using the NG,NG-dimethyl arginine-agarose. This antibody is useful for detection, isolation and localization of proteins/peptides with asymmetric dimethylated arginine residues.

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.

Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is one year from date of shipping if properly stored.

1. J. Proteome Res. 2013. 12 (9): 3884-3899. doi:10.1021/pr400556c
2. Proteomics. 2016. 16 (3): 465-476. doi: 10.1002/pmic.201400564
3. Proteomics. 2013. 13 (7): 1059-1064. doi: 10.1002/pmic.201200477
4. Proteomics.  2015. 15 (18): 3209-3218. doi: 10.1002/pmic.201500075
5. J. Neurosci. 2015. 35 (37): 12890-12902. doi: 10.1523/JNEUROSCI.0246-15.2015
6. The FEBS Journal. 2019. doi: 10.1111/febs.15057
7. J Exp Clin Cancer Res 42, 261 (2023). doi: 10.1186/s13046-023-02835-6