This antibody is developed using glutathione (GSH)-KLH conjugate, and purified with antigen-specific affinity chromatography. The antibody is conjugated to horseradish peroxidase (HRP) via reductive amination. Glutathione antibody, HRP, can detect and quantify reduced (GSH) and oxidized (GSSG) glutathione, as well as glutathionylated proteins/peptides.

Glutathione is a tripeptide. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. Glutathione, an antioxidant, protects cells from toxins such as free radicals. Glutathione can also modify proteins via disulfide bonds. Redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes have been reported.

Product is stable for several weeks at 4°C. For extended storage, store product at –20ºC. Expiration date is six months from date of shipping if properly stored.

1. PNAS. 2005. 102(39): 13998-14003. doi:10.1073/pnas.0504398102
2. J. Biol. Chem. 2007. 282(45): 32640-54. doi:10.1074/jbc.M702953200