p53 Antibody(ICP7110)

Applications:
ELISA (1:2500); WB (1:2500)
Specificity:
The antibody recognizes human p53 in cell and tissue.
Immunogen:
Human phosphor p53 peptide (15-40 aa) KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in PBS, pH 7, with 50 % glycerol
Pack Size
Price (USD)
Quantity
100 μg
$295.00
In Stock Request a Bulk Order
  • Product Description

    These antibodies were developed based on human p53 sequences (25-40 aa). It was tested to detect human p53 in human cell and tissue.
  • Specificity

  • Applications

  • Scientific Description

    P53 (tumour protein 53 or TP53) regulates the cell cycle by acting as a transcription factor. It suppresses tumours and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman". This refers to its role in conserving stability by preventing genome mutation. P53 refers to its molecular mass (53 kDa) on SDS-PAGE.

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

    1. 1. Strachan T. et al. Human Molecular Genetics 2. Ch. 18, 1999 Cancer Genetics.
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