Stat1 Antibody(ICP6010)

Applications:
ELISA; WB; IHC
Specificity:
The antibody recognizes Stat1 from human and mouse.
Immunogen:
Human Stat1 peptide KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in PBS, pH7 with 50% glycerol
Pack Size
Price (USD)
Quantity
100 µg
$295.00
In Stock Request a Bulk Order
  • Product Description

    The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ. These antibodies were raised based on the human Stat1 sequence (690-720 aa) and tested in western blotting of human and mouse cell lysate and mouse tissue (spleen) extract to detect Stat1.
  • Scientific Description

    STAT1 and STAT2 were the first two STAT (signal transducers and activators of transcription) proteins discovered. They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction. Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6.[1] Specific functions of the STAT proteins are poorly understood. They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

    1. Cell, 1996. 84(3): 331-334. doi:10.1016/S0092-8674(00)81277-5
    2. Eur. J. Biochem. 1997. 248(3): 615-633, doi:10.1111/j.1432-1033.1997.00615.x
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