p53 Antibody, HRP(ICP7115)

Applications:
ELISA (1:2500); WB (1:2500)
Specificity:
The antibody recognizes human p53 in cell and tissue.
Immunogen:
Human p53 peptide (15 - 40 aa) KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in stabilized buffer with 50% glycerol
Conjugation:
Reductive amination; HRP/Ab ratio - 2:1
Pack Size
Price (USD)
Quantity
100μg
$375.00
In Stock Request a Bulk Order
  • Product Description

    This antibody was developed and affinity purified using a peptide based on the human p53 sequence (4-40 aa) . The antibody was conjugated to peroxidase (HRP) via reductive amination. It was tested to detect the human p53 specifically in human cell and tissue. Direct labeling of peroxidase of the primary antibody is believed to avoid the effect of the IgG (50-60 kDa) signal from the use of secondary antibodies.
  • Specificity

  • Applications

  • Scientific Description

    P53 (tumour protein 53 or TP53) regulates the cell cycle by acting as a transcription factor. It suppresses tumours and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman". This is referring to its role in conserving stability by preventing genome mutation. P53 refers to its molecular mass (53 kDa) on SDS-PAGE.

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C.Expiration date is six months from date of shipping if stored properly.

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