Acetyl Lysine Antibody, Biotin(ICP0383)

Specificity:
The antibody recognizes proteins acetylated on lysine residues. Tested: acetylated histone, acetylated BSA, and acetylated MBP. No cross-reaction to non-acetylated proteins.
Immunogen:
Acetylated KLH conjugate.
Species:
Rabbit
Formulation:
250 µg/mL antibody in PBS, pH 7, with 50% glycerol.
Conjugation:
Acylation with NHS-biotin; biotin:Ab molar ratio = 10:1
Pack Size
Price (USD)
Quantity
100 µg
$375.00
In Stock Request a Bulk Order
  • Product Description

    The affinity purified polyclonal rabbit anti-acetylated lysine antibody is developed using acetylated KLH as the immunogen. The acetylated lysine-specific antibody is conjugated with d-Biotin via amine acylation.
  • Scientific Description

    DNA transcription cannot take place unless DNA is unwound from the nucleosomes. The cell unwinds the DNA by acetylating the lysine residues within the proteins. It has been suggested that acetylation of non-histone proteins (e.g. transcription factors) and histones may be involved. Acetylation of the proteins may result in signal transduction within the chromatic domains.
  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

    1. FEBS Lett. 2002. 513(1): 124-128. doi:10.1016/S0014-5793(01)03309-9.
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