Phospho-AKT (Ser473) Antibody(ICP0453)

Applications:
ELISA (0.25 µg/mL); WB (1 µg/mL); IP (10 µg/2 mg crude protein)
Specificity:
Recognizes phosphorylated PKB on serine 473. There are no cross reactions with the non-phosphorylated PKB.
Immunogen:
Human PKB C-terminal peptide that is based on human PKB-KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in PBS, 50% glycerol
Pack Size
Price (USD)
Quantity
100 μg
$375.00
In Stock Request a Bulk Order
  • Product Description

    PKB alpha (AKT1) is a member of the PKB family, which is responsive to cell activation. The anti-PKB alpha antibodies were raised with a peptide based on the sequence of the human PKB C-terminal end and affinity purified with the same peptide on agarose. The affinity purified antibodies are useful for detection and isolation of PKB alpha from cell lysates.
  • Specificity

  • Applications

  • Scientific Description

    AKT is also known as protein kinase B (PKB). It is an important molecule in mammalian cellular signalling. It inhibits apoptotic processes and is involved in cellular survival pathways. It also induces protein synthesis pathways.

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

    1. 1. J. Clin. Invest. 2003. 112: 197-208. doi:10.1172/JCI16885
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