P70 S6K Antibody(ICP9830)

Applications:
ELISA; WB; IP
Specificity:
Recognizes p70 S6K of human, mouse, and rat.
Immunogen:
Human p70 S6K C-terminal peptide (ISKRPEHLRMNL)-KLH conjugates
Species:
Rabbit
Formulation:
250 µg/mL in TBS, 0.01% NaN3
Pack Size
Price (USD)
Quantity
100 µg
$295.00
In Stock Request a Bulk Order
  • Product Description

    p70 S6K is a ribosome S6 kinase. Affinity purified rabbit polyclonal anti-p70 S6K is developed using a C-terminal peptide based on human p70 S6K (C-ISKRPEHLRMNL).
  • Specificity

  • Applications

  • Scientific Description

    p70 S6K is a protein serine/threonine kinase that exists ubiquitously. [1] p70 S6K affects the activities of the cell cycle. p70 S6K is an important regulator of cell proliferation. [2] p70 S6K activation requires sequential phosphorylation at proline-directed residues in the putative auto-inhibitory pseudo-substrate domain, as well as threonine 389. Activation of p70 S6K requires phosphoinositide 3-kinase (PI3-K)-dependent signal(s).

  • Storage & Stability

    Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

  • Product Specific References

    1. Crit. Rev. Biochem. Mol. Biol. 1994. 29(6): 385-413.
      doi:10.3109/10409239409083485
    2. J. Biol. Chem. 1996. 271(2): 963-971. doi:10.1074/jbc.271.2.963
    3. Mol. Cell Biol. 1999. 19(4): 2921-2928.
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