One of the members of mitogen-activated protein kinases is called p44 MAP Kinase (Erk1). It participates in cell growth and differentiation. [1,2] By phosphorylating transcription factors, p44 MAP kinase regulates meiosis and mitosis of the cells. In the case of human MAP kinase, Erk1 activates Elk-1 through phosphorylation of threonine 202 and tyrosine 204. It is also known that Erk1 autophosphorylates tyrosine. [3]

Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

1. EMBO J. 1991. 10: 885–892. doi:10.1002/j.1460-2075.1991.tb08021.x
2. Mol Cell Biol. 1993. 13: 4679–4690. doi:10.1128/MCB.13.8.4679
3. Cell. 1995. 80: 179–185. doi:10.1016/0092-8674(95)90401-8