NG-monomethyl Arginine Antibody (anti-mMeR), HRP was raised from rabbits that were immunized with NG-monomethyl arginine-KLH conjugates. This antibody was specifically isolated and affinity purified using the monomethyl-arginine antigen. The affinity purified methyl arginine antibodies are then conjugated to horseradish peroxidase (HRP) and are useful for detection, isolation and localization of proteins with NG-methylated arginine residues.

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes including protein trafficking, signal transduction and transcriptional regulation.

Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is six months from date of shipping if stored properly.

1. Mol Microbiol. 2007. 65: 590-606. doi:10.1111/j.1365-2958.2007.05831.x