Dimethyl (sym) arginine antibody is raised from rabbits immunized with NG,NG′-dimethyl-L-arginine-KLH, and affinity purified using the NG,NG′-dimethyl-L-arginine-agarose column. This antibody is useful for detection, isolation and localization of proteins/peptides with symmetric dimethylated arginine residues.

Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified in such a way possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes, including protein trafficking, signal transduction and transcriptional regulation.

Product is stable for several weeks at 4°C. For extended storage, aliquot content and store product at -20°C. Avoid cycles of freezing and thawing. Expiration date is one year from date of shipping if stored properly.

1.  J. Neurosci. 2015. 35(37): 12890-12902. doi:10.1523/JNEUROSCI.0246-15.2015.