ImmuneChem’s Acetyl Lysine Antibody (ICP0380) was used in the Immunoblotting and co-immunoprecipitation experiments to detect the presence of acetylation of FOXO and histone H4 by KAT8 to make DNA accessible for Atg8 transcription for autophagy.
Liu. T-W., Zhao. Y-M., Jin. K-Y., et al. KAT8 is upregulated and recruited to the promoter of Atg8 by FOXO to induce H4 acetylation for autophagy under 20-hydroxyecdysome regulation. J. Biol. Chem. 2024. 300(3): 105704.