Scientists have found that the PINK1-PKA-NCLX axis plays an important role in mitochondrial calcium efflux in cardiomyocytes with the help of ImmuneChem's PKA Kinase Assay Kit, Type I | Immunechem

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Scientists have found that the PINK1-PKA-NCLX axis plays an important role in mitochondrial calcium efflux in cardiomyocytes with the help of ImmuneChem’s PKA Kinase Assay Kit, Type I

Scientists have found that the PINK1-PKA-NCLX axis plays an important role in mitochondrial calcium efflux in cardiomyocytes with the help of ImmuneChem’s PKA Kinase Assay Kit, Type I

January 10th, 2023

In the journal Stem Cell Research & Therapy, researchers used ImmuneChem’s PKA Kinase Assay Kit, Type I (ICP0216) to observe PKA activity and help determine the role PINK1 in regulating NCLX-mediated mCa2+ efflux.

Zhou. Q., Xie. M., Zhu. J., et al. PINK1 contained in huMSC-derived exosomes prevents cardiomyocyte mitochondrial calcium overload in sepsis via recovery of mitochondrial Ca2+ efflux. Stem Cell Research & Therapy. 2021. 12: 269.